In terms of scheme fit, Tuipulotu would likely be best suited for a 4-3 defense that allows him to play both defensive tackle and defensive end positions. His ability to disrupt plays in the backfield and rush the passer would make him a valuable asset in both positions. He may also be able to contribute as a 3-4 defensive end, although he would likely need to add some more size and strength to hold up against the run at that position.